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Obesity has been associated with poorer cognitive function, including poorer hippocampal function. One potential mechanism related to both obesity and hippocampal function may be related to decreased intake and neural concentration of lutein. Lutein is a carotenoid that accumulates in neural tissue at concentrations up to 5 times more than other carotenoids. Lutein has been found to influence hippocampal-dependent memory performance, possibly via its antioxidant and anti-inflammatory effects.

Antibiotics alter the microbial balance of the intestines and can lead to antibiotic-associated diarrhea. To assess the efficacy and safety of probiotics for the prevention of antibiotic-associated diarrhea in children, researchers conducted a systematic review and meta-analysis. The analysis was published in 2019 in the Cochrane Database of Systematic Reviews.

Type 2 diabetes is characterized by insulin resistance and hyperglycemia, which contribute to the formation of reactive oxygen species, increased platelet aggregation, and a higher risk of cardiovascular disease. Multiple nutritional supplements have been evaluated in the context of type 2 diabetes, including alpha-lipoic acid (ALA), carnosine, and thiamine.

Fatigue is one of the most common consequences of chronic illnesses or the treatment of chronic illnesses. Many individuals attempt to improve their energy by using natural products, with one of the most popular products being ginseng. Both Asian ginseng root (Panax ginseng) and American ginseng root (Panax quinquefolius) contain ginsenosides, which have antioxidant, anti-inflammatory, and cortisol-modulating effects.

During an acute allergic reaction, production of reactive oxygen species (ROS) contributes to an inflammatory cascade and histamine release. Vitamin C (ascorbate) might mitigate the allergic cascade by counteracting oxidative stress and reducing histamine. Intravenous (IV) administration of vitamin C is the most effective way to elevate the plasma concentration of ascorbate and is often used as a complementary treatment in the management of inflammatory diseases.